Madrigal Pharmaceuticals: a leader in MASH treatment with significant growth potential

Madrigal Pharmaceuticals $MDGL entered 2024 with significant success when it launched its first approved drug, Rezdiffra, for the treatment of metabolic steatohepatitis (MASH). This unique drug helps patients with moderate to advanced liver fibrosis, giving Madrigal a privileged position in a market where it currently has no competition. The company is showing promising growth and represents an exciting opportunity for investors with a long-term horizon.

Exclusive market and growing sales

Since the launch of Rezdiffra in March 2024, the company has managed to achieve sales of $62.2 millionin the third quarter , indicating rapid commercial adoption. The drug is currently being used by more than 6,800 patients and this number is increasing rapidly, contributing to the sales growth. Madrigal $MDGL expects to gain approval in the European Union in the second half of 2025, which could be a significant boost to further expansion.

Financial stability and profitability expectations

The company has so far achieved operating expenses of $178.5 million for the third quarter, with $1 billion in cash and investments. Madrigal $MDGL thus has sufficient funds to support its growth and achieve profitability without having to seek additional financing. This provides investors with confidence that the company has a strong foundation for steady growth.

Competitive landscape and potential of Rezdiffra

Although competitors such as Novo Nordisk and Eli Lillyare expected to enter the MASH market , Madrigal $MDGL is likely to maintain its position due to the advantages in tolerability of Rezdiffra and its long-term efficacy. While Novo Nordisk's semaglutide has been successful in other diseases, its efficacy and tolerability in treating MASH may be worse than that of Rezdiffra. In addition, Madrigal $MDGL has a chance of faster approval for broader indications, which could further boost its market share.

Long-term investment opportunity

Thus,Madrigal Pharmaceuticals $MDGL offers an attractive opportunity for investors who are prepared to hold their shares for at least a few years. With its current market lead, growing demand for MASH drugs, and stable financials, this biotech company has the potential to continue to grow and expand its portfolio.


I read now that Trump has appointed a new Health Secretary and he is not supporting and fighting against such companies, so we'll see how this plays out now.

I would probably be more interested in $MRNA or $PFE.

I had $PFE in my portfolio and that was enough. I recently sold $PFE and I definitely won't be looking to have that sector represented in my portfolio anytime soon😃.

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