Summary
State Street SPDR S&P Pharmaceuticals ETF is an ETF - a fund traded on an exchange like a stock - run by SPDR. Positions inside: 63. The ten largest make up 23% of the fund.
- Yearly costs
- 0.35%
- Fund size
- $451.1M
- Positions
- 63
- Dividend yield
- 0.44%
- Running since
- 2006
What speaks for it
- Costs of 0.35% a year are below the middle of comparable funds (0.44%).
- It has been running since 2006.
What to watch
- 100% of the fund is in one sector (Healthcare).
- 96% of the fund is in one country (United States).
- In the last five years its price once dropped by 37% from its high.
A fund has no Bulios Score and no Fair Price of its own - both are computed from the results of a single company. This page shows what is inside the fund and what it costs instead.
Price
Performance
- 1 month
- -7.0%
- 3 months
- -7.2%
- This year
- +11%
- 1 year
- +27%
- 3 years
- +69%
- 5 years
- +29%
- 10 years
- +46%
- Avg. market cap
- $61.5B
- P/E
- 15.5x
- Forward P/E
- 11.6x
- P/S
- 2.5x
- P/B
- 3.0x
- P/FCF
- 11.8x
- EV/EBITDA
- 8.7x
- Dividend yield
- 0.73%
- ROIC
- -1.7%
- ROE
- -7.9%
- Gross margin
- 74.6%
- Operating margin
- -146.7%
- Net margin
- -130.5%
- Payout ratio
- 11.4%
- Net debt/EBITDA
- 3.6x
- Beta
- 0.72
Weighted average of the 50 largest companies, which make up 92% of the fund. Banks and insurers are left out of the gross margin, the ROIC and the EBITDA figures.
What is inside?
Widely spread- 1 XEXeris Biopharma Holdings, Inc. XERS 2.7%
- 2 PCPacira BioSciences, Inc. PCRX 2.6%
- 3 MAVeradermics, Incorporated MANE 2.4%
- 4 PRPerrigo PRGO 2.4%
- 5 AMAmneal Pharmaceuticals AMRX 2.3%
- 6 LLEli Lilly LLY 2.3%
- 7 VTViatris VTRS 2.3%
- 8 ZTZoetis ZTS 2.2%
- 9 PFPfizer PFE 2.2%
- 10 LGLigand Pharmaceuticals LGND 2.1%
Positions in the fund: 63. The ten largest make up 23% of it.
Composition as of Oct 18, 2026.
Where is it spread?
One sector dominatesBy sector
- Healthcare 100%
By country
- United States 96%
- Ireland 4.2%
- Other countries 0.09%
By company size
- Mega cap 6.2%
- Large cap 16%
- Mid cap 32%
- Small cap 44%
- Micro cap 1.6%
By the company's market value: Mega cap from $200B, Large cap from $10B, Mid cap from $2B, Small cap from $300M, Micro cap below $300M.
Largest sector: Healthcare (100%). Largest country: United States (96%). Largest size group: Small cap (44%).
What does it cost me?
Cheap- A year from $10,000
- $35.00
- Over 20 years
- $1,714
From every $10,000 invested the fund takes $35.00 a year. You do not pay it separately - it is taken out of the fund's value. Over 20 years at 5% yearly growth that adds up to about $1,714.
How has it done?
Growing slowly- A year on average, 10 years
- +3.9%
- Deepest drop
- -37%
- Yearly volatility
- 23%
Average yearly growth over the last ten years: 3.9%. Deepest drop in these years: 37% below the earlier high.
Does it pay dividends?
Yes, it pays out- Yield
- 0.44%
- Payments a year
- 4
- Last payment
- $0.04
Over the last 12 months it paid $0.27 per share, which is 0.44% of today's price. The last payment was $0.04 on Sep 21, 2026.
Is it easy to buy and sell?
Yes- Traded a day
- $9.28M
- Shares a day
- 149K
On an average day about $9.28M of the fund changes hands.
How expensive are the companies inside?
Usual valuation- P/E of the companies inside
- 15.5
- Average Bulios Score
- 52 out of 100
Weight by Bulios Fair Price
- Undervalued 35%
- Fairly valued 11%
- Overvalued 54%
On average the companies inside trade for 15.5 times their yearly profit. By Fair Price, 54% of the rated weight comes out as overvalued.
Counted from its largest companies (50), which make up 92% of the fund. Each company counts by its weight. We use the metrics, the Bulios Score and the Fair Price of the companies themselves.
Similar funds
Funds that hold much of the same. The overlap says how much of their weight they share with this fund.
| Fund | Domicile | Size | 1-year change | Dividends | ||
|---|---|---|---|---|---|---|
PI PILL Direxion Daily Pharmaceutical & Medical Bull 3X ETF | United States | 1.22% | $27.8M | +60% | Pays out | 71% |
IH IHE iShares U.S. Pharmaceuticals ETF | United States | 0.37% | $1.14B | +34% | Pays out | 40% |
PJ PJP Invesco Pharmaceuticals ETF | United States | 0.58% | $361.1M | +30% | Pays out | 37% |