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BlackRock Health Sciences Opportunities Portfolio Service Shares SHISX · NASDAQ

$68.84 +0.48% (+$0.33)

Summary

BlackRock Health Sciences Opportunities Portfolio Service Shares is a mutual fund run by BlackRock. It does not trade on an exchange: you buy it from the fund company at a price set once a day. Positions inside: 138. The ten largest make up 55% of the fund.

Yearly costs
1.16%
Fund size
$6.59B
Positions
138
Dividend yield
13.77%
Running since
2005

What speaks for it

  • A large fund with $6.59B under management.
  • It has been running since 2005.

What to watch

  • The ten largest positions make up 55% of the fund, so its result rests on a few names.
  • 100% of the fund is in one sector (Healthcare).
  • Costs of 1.16% a year are above the middle of comparable funds (0.40%).

A fund has no Bulios Score and no Fair Price of its own - both are computed from the results of a single company. This page shows what is inside the fund and what it costs instead.

Price

Performance

1 month
+8.7%
3 months
+9.3%
This year
+8.0%
1 year
+8.1%
3 years
+13%
5 years
-10%
10 years
+48%
Avg. market cap
$242.4B
P/E
39.4x
Forward P/E
-
P/S
2.6x
P/B
5.9x
P/FCF
26.1x
EV/EBITDA
21.9x
Dividend yield
0.95%
ROIC
5.8%
ROE
17.8%
Gross margin
66.8%
Operating margin
-55.5%
Net margin
-28.4%
Payout ratio
37.6%
Net debt/EBITDA
2.1x
Beta
0.49

Weighted average of the 50 largest companies, which make up 71% of the fund. Banks and insurers are left out of the gross margin, the ROIC and the EBITDA figures.

What is inside?

Concentrated
  1. 1 ELI LILLY 12%
  2. 2
    JN
    Johnson & Johnson JNJ.TO 8.1%
  3. 3
    MR
    Merck & Co. MRK 5.6%
  4. 4
    AB
    AbbVie Inc. ABBV.BA 5.3%
  5. 5
    TM
    Thermo Fisher Scientific Inc. TMO.TO 4.9%
  6. 6
    GI
    Gilead Sciences, Inc. GILD.TO 4.2%
  7. 7
    AM
    Amgen AMGN 4.0%
  8. 8
    UN
    UnitedHealth Group Incorporated UNH.BA 3.9%
  9. 9 DANAHER 3.5%
  10. 10
    VR
    Vertex Pharmaceuticals VRTX 3.3%

Positions in the fund: 138. The ten largest make up 55% of it.

Composition as of Nov 7, 2026.

Where is it spread?

One sector dominates

By sector

By country

By company size

By the company's market value: Mega cap from $200B, Large cap from $10B, Mid cap from $2B, Small cap from $300M, Micro cap below $300M. Counted from the companies that make up 75% of the fund.

Largest sector: Healthcare (100%). Largest country: United States (72%). Largest size group: Mega cap (49%).

What does it cost me?

Expensive
A year from $10,000
$116
Over 20 years
$5,286

From every $10,000 invested the fund takes $116 a year. You do not pay it separately - it is taken out of the fund's value. Over 20 years at 5% yearly growth that adds up to about $5,286.

How has it done?

Growing slowly
A year on average, 10 years
+4.0%
Deepest drop
-30%
Yearly volatility
21%

Average yearly growth over the last ten years: 4.0%. Deepest drop in these years: 30% below the earlier high.

Does it pay dividends?

Yes, it pays out
Yield
13.77%
Payments a year
1
Last payment
$6.46

Over the last 12 months it paid $9.48 per share, which is 13.77% of today's price. The last payment was $6.46 on Jul 22, 2026.

How expensive are the companies inside?

Rather expensive
P/E of the companies inside
39.4
Average Bulios Score
51 out of 100

Weight by Bulios Fair Price

On average the companies inside trade for 39.4 times their yearly profit. By Fair Price, 61% of the rated weight comes out as overvalued.

Counted from its largest companies (50), which make up 71% of the fund. Each company counts by its weight. We use the metrics, the Bulios Score and the Fair Price of the companies themselves.

Can I buy it as an ETF?

A mutual fund is bought from the fund company. These ETFs hold much of the same and trade on an exchange, so an ordinary broker carries them.

Fund Domicile Size 1-year change Dividends
PB
PBPH Portfolio Building Block World Pharma and Biotech Index ETF
United States 0.13% $13.6M - - 34%
BM
BMED iShares Health Innovation Active ETF
United States 0.77% $14.5M +31% Pays out 26%
VH
VHT Vanguard Health Care ETF
United States 0.09% $18.6B +27% Pays out 25%
FH
FHLC Fidelity MSCI Health Care Index ETF
United States 0.08% $3.95B +27% Pays out 24%
IY
IYH iShares U.S. Healthcare ETF
United States 0.37% $4.72B +28% Pays out 24%
ZP
ZPDH.DE State Street SPDR S&P U.S. Health Care Select Sector UCITS ETF (Acc)
Ireland 0.15% $648.2M +34% Reinvests 23%

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